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Chewing while your mouth is numb could result in a bite injury to your tongue, lips, or inside of your cheek. All Consumer Professional Pill ID Interactions News FDA Alerts Approvals Pipeline Clinical Trials Care Notes Encyclopedia Dictionary Natural Products. The federal Omnibus Budget Reconciliation Act OBRA regulates medication use in residents of long-term care facilities. Out of your order profit we share a large percentage to acquire medicines for poor people and their treatment. Alfentanil: Due to the CNS depression potential of local anesthetics, they should be used with caution with other agents that can cause respiratory depression, such as opiate agonists. This action decreases the rate of membrane depolarization, thereby increasing the threshold for electrical excitability.